And the Spaniard has been given a testing opening to Premier League management.
But the former Paris Saint-Germain and Sevilla coach has been given a daunting task at the outset of his reign, with Arsenal kicking off the 2018-19 season at home to Pep Guardiola's champions on the weekend beginning August 11 before then travelling to Stamford Bridge to face Chelsea a week later.
They will then play another away game at Watford on September 1 before the global break after the Hornets agreed to reverse the fixture.
United do at least get to kick-off the new Premier League season at home when Leicester City visit Old Trafford on August 11, before an away trip to Brighton and then another home match against Spurs.
A similar result on the opening day would certainly issue a statement of City's intent.
Liverpool begin their season at home to West Ham United, with Manuel Pellegrini taking charge of the Hammers for the first time.
The first Manchester derby takes place at City's Etihad Stadium on November 10, with the second at Old Trafford on March 16.
A journey down to Southampton follows on 29 December and we bring in the New Year with a mouth-watering visit of Liverpool on 1 January.
Fulham's first game back in the Premier League sees former boss Roy Hodgson make the short trip across London with his Crystal Palace side.
Wolves, Cardiff and Fulham replace Swansea, Stoke and West Brom in the top flight.
Spurs petitioned to play their first four games away from home, similarly to Liverpool last season before the opening of their new main stand.
Oddly, for the third consecutive season, we lock horns with Arsenal and Chelsea in consecutive games.
All dates are provisional and subject to TV requirements.