Jesse Lingard and Scott McTominay may return from injury, but Mourinho's anger at the treatment of his players on global duty was clear after he had to cope with a depleted squad for the Champions League loss to Juventus.
Meanwhile former Manchester United midfielder, Paul Ince says the coach should be sacked.
"And I didn't think, given the dynamic of the game, it would have been appropriate to put him on". "Then after two weeks we lost Dalot, Fellaini, Alexis, we lost McTominay".
"At this moment we are not in the best situation to think about resting players or trying to find solutions".
Sanchez and Fellaini are carrying groin problems, while McTominay suffered a minor knee injury and Dalot picked up a knock.
'Then he came back and was injured again and he is the kind of player that needs to be really really sharp'.
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Manchester United boss Mourinho has seen Lingard struggle for fitness in the wake of his heroics with England at the World Cup in Russian Federation.
Speaking at a news conference ahead of Sunday's Premier League match against Everton, the United boss was asked about the possibility and simply replied: "No".
"So now he's going back and doing the work to try to be 100 per cent [fit] and, in this moment, he's nearly there, because of the team's needs".
Here are three things we learnt from the match. That's the question we have to answer tomorrow [Saturday] or if we wait one more week and give one more week of stability to the work, so he can be back next week.
"I am really happy to play for this club, one of best clubs in the world, so for me really good to be part of this club".